| Chemotherapy Protocols |
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| Protocol |
CAV (VAC) |
| Cancer |
Small Cell Lung Cancer |
| CAV (VAC) |
Cyclophosphamide |
750 - 1000 mg/m2 i.v, day 1 |
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Doxorubicin |
50 mg/m2 i.v. day 1 |
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Vincristine |
1.4 mg/m2 (max 2 mg) i.v. day 1 |
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Repeat cycle every 21 days |
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| Protocol |
CHOP |
| Cancer |
Non-Hodgkin’s lymphoma |
| CHOP |
Cyclophosphamide |
750 mg/m2 i.v, day 1 |
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Doxorubicin |
50 mg/m2 i.v. day 1 |
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Vincristine |
1.4 mg/m2 (max 2 mg) i.v. day 1 |
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Prednisone |
100 mg/day p.o. days 1-5 |
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Repeat cycle every 21 days |
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| Protocol |
COP |
| Cancer |
Non-Hodgkin’s lymphoma |
| COP |
Cyclophosphamide |
800-1000 mg/m2 i.v, day 1 |
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Vincristine |
1.4 mg/m2 (max 2 mg) i.v. day 1 |
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Prednisone |
60 mg/m2 p.o. days 1-5 |
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Repeat cycle every 14 days |
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| Protocol |
MACOP-B |
| Cancer |
Non-Hodgkin’s lymphoma |
| MACOP-B |
Methotrexate |
400 mg/m2 i.v, weeks 2, 6 & 10 |
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Leucovorin |
15 mg/m2 p.o. every 6 hours for 6 doses, beginning 24 hours after methotrexate |
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Doxorubicin |
50 mg/m2 i.v. weeks 1, 3, 5, 7, 9 & 11 |
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Cyclophosphamide |
350 mg/m2 i.v. weeks 1, 3, 5, 7, 9 & 11 |
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Vincristine |
1.4 mg/m2 (max 2 mg) i.v. weeks 2, 4, 6, 8, 10 & 12 |
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Prednisone |
75 mg/day p.o. for 12 weeks, then taper over last 2 weeks |
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Bleomycin |
10 units/m2 i.v. weeks 4, 8 & 12 |
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Co-Trimoxazole |
1 tabl 2 times per day for 12 weeks |
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Ketoconazole |
200 mg/day p.o. |
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administer 1 cycle |
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| Protocol |
MOPP |
| Cancer |
Adult Hodgkin’s disease |
| MOPP |
Mechloretamine |
6 mg/m2 i.v. days 1 & 8 |
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Vincristine |
1.4 mg/m2 (max 2 mg) i.v. days 1 & 8 |
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Procarbazine |
100 mg/m2 p.o. days 1-14 |
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Prednisone |
40 mg/m2 p.o. days 1-14 |
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repeat cycle every 28 days |
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| Protocol |
MOPP/ABV hybrid |
| Cancer |
Hodgkin’s disease |
| MOPP/ABV hybrid |
Mechloretamine |
6 mg/m2 i.v. day 1 |
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Vincristine |
1.4 mg/m2 (max 2 mg) i.v. day 1 |
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Procarbazine |
100 mg/m2 p.o. days 1-7 |
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Prednisone |
40 mg/m2 p.o. days 1-14 |
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Doxorubicin |
35 mg/m2 i.v. day 8 |
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Bleomycin |
10 units/m2 day 8 |
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Vinblastine |
6 mg/m2 i.v. day 8 |
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repeat cycle every 28 days |
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| Protocol |
VBMCP |
| Cancer |
Multiple Myeloma |
| VBMCP |
Vincristine |
1.2 mg/m2 (max 2 mg) i.v. day 1 |
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Carmustine |
20 mg/m2 i.v. day 1 |
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Procarbazine |
8 mg/m2 p.o. days 1-4 |
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Prednisone |
400 mg/m2 i.v. day 1 |
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Doxorubicin |
40 mg/m2 p.o. days 1-7 all cycles, and 20 mg/m2 p.o. days 8-14 first 3 cycles only |
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repeat cycle every 35 days |
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