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Chemotherapy Protocols
Bleomycin
Carboplatin
Cisplatin
Doxorubicin
Etoposide
Vincristine
Protocol
PC
Cancer
Ovarian Cancer
Reference
Zamagni1, Higgins2
PC
paclitaxel
175 mg/m² or 200 mg/m² over 3 hr, day 1
carboplatin
400 mg/m²(4) or AUC 5-6.5 over 30 min., day 1
every 3-4 weeks, 6 cycles
Protocol
CE
Cancer
Small Cell Lung Cancer
Reference
Evans3, Okamoto4
CE
carboplatin
300 mg/m² in 20’-30’ or AUC5 over 1 hr 7, day 1
etoposide
100 mg/m² over 30-60 min., day 1-3
every 4 weeks, 4-6 cycles
Protocol
CE
Cancer
Non Small Cell Lung Cancer
Reference
Helsing5
CE
carboplatin
300 mg/m2 day 1
etoposide
120 mg/m2 orally, day 1-5
every 4 weeks, maximum of 8 cycles
Protocol
PC
Cancer
Non Small Cell Lung Cancer
Reference
Hainsworth6, Helsing7
PC
paclitaxel
200 mg/m² or 225 mg/m² over 1 hr, day 1
carboplatin
AUC 5 or AUC 6 over 30-60 min., day 1
every 3-4 weeks, 6 cycles
Protocol
M-CAVI
Cancer
Transitional Cell Cancer of Urothelium
Reference
Bellmunt8
M-CAVI
methotrexate
30 mg/m² in slow push, day 1, 15, 22
carboplatin
AUC 5 over 30 min., day 2
vinblastine
3 mg/m² in slow push, day 2, 15, 22
every 4 weeks
Protocol
PC
Cancer
Transitional Cell Cancer of Urothelium
Reference
Zielinski9
PC
paclitaxel
175 mg/m² over 3 hrs, day 1
carboplatin
AUC 5 over 1hr, day 1
every 3 weeks, 6 cycles
References:
1. C. Zamagni et al. Am. J. Clin. Oncol. 21 (1998) 491-7.
2. R.V. Higgins et al. Gynecol. Oncol. 75 (1999) 464-7.
3. W.K. Evans et al. Br. J. Cancer 58 (1988) 464-8.
4. H. Okamoto et al. J. Clin. Oncol. 17 (1999) 3540-5.
5. M. Helsing et al. Eur. J. Cancer 34 (1998) 1036-44.
6. J.D. Hainsworth et al. Eur. J. Cancer 34 (1998) 654-8.
7. M. Helsing et al. Lung Cancer 24 (1999) 107-13.
8. J. Bellmunt et al. Cancer 80 (1997) 1966-72.
9. C.C. Zielinski et al. Br. J. Cancer 78 (1998) 370-4.
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